The Director, Cell & Gene Quality, International will support defining the strategy for the international expansion of Cell & Genetic programs. The role will establish the quality risk management plans, work closely with cross functional QA, CMC, External manufacturing, Supply Chain and Commercial teams to ensure QA oversight is maintained. Key activities include develop,

Lead the design and execution of experiments, together with the team, to evaluate new medium components and supplements, confirm the cell culture performance. Align with leadership to develop strategic roadmap on continuous medium optimization and phase appropriate medium development and implementation. Manage the medium development team to ensure timely delivery of cell

The Associate Director, Modeling & Simulation will combine strong pharmacometric skills with deep biological understanding toindependently determine, plan, and execute M&S analyses in close collaboration with cross functional colleagues within the R&D organization. This incumbent determines, plans, and executes technically challenging analyses b y using state of the art M

The Manager of FP&A is a key member of Vertex's Finance business partner organization, supporting the Global Clinical Operations (GCO) function by providing financial direction and insight including identification of key value drivers and Business KPIs, helping GCO deliver their short term and long term goals through proactive day to day support, challenge, influence and

Support select branded and unbranded tactics for the Institutional & IDN channel, including strategic engagements, channel convention support, team meeting & training support, market research, and advisory board formation Lead the IDN and institution strategic council Develop and execute branded 548 assets that effectively position the brand in the institution; this inclu

Responsibility to build and execute the Global Medical strategy for key CF products. Communicate the Global Medical strategy to partner functions and senior leaders for further strategic and tactical guidance. Execute the Global components of the medical strategy plan. Partner with Clinical Development, HEOR, RWE, Regional Medical Affairs and partner functions to identify

The Senior Medical Science Liaison (Sr MSL) will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex' compounds in a timely, ethical and stakeholder foc

Vertex seeks a talented scientist to join the Vertex Cell and Genetic Therapies (VCGT) Cell therapy and Immunology team at The Jeffrey Leiden Center for Cell and Genetic Therapies in Boston, MA. The team's mission is to discover and actualize the next generation of cell therapies for patients with type 1 diabetes, sickle cell disease and Duchenne muscular dystrophy. We ar

This Scientist will support Vertex's drug development programs by applying conceptual knowledge to understand various relationships between fundamental materials properties, pharmaceutical processing conditions, and final product performance and quality attributes. The role will have a proven track record of applying conceptual knowledge of materials science and engineeri

Establishes meaningful and professional relationships within key accounts across multiple layers of the hospital system (key hospital medical and administrative staff, pharmacies, formulary decision makers and KTLs) Develops and maintains expertise on the product's clinical attributes and patient unmet need and educates healthcare professionals on product use in appropria

Vertex is in an exciting time of growth and innovation, and technology and data are valued as strategic assets. The Data & Software Engineering team in the Data, Technology and Engineering (DTE) organization is seeking an experienced technology leader to help devise, oversee, and implement the technology strategy for master data management and data governance across the e

The Associate Medical Director will serve as the Medical Lead for Vertex clinical trials in Cystic Fibrosis (CF), working with cross functional multidisciplinary study teams on clinical trial strategy, design and execution and serving as the primary Medical Monitor responsible for monitoring the safety of enrolled subjects on assigned trials. This individual will work on

Acts as main point of contact for CDMO(s), building and maintaining strategic relationships within the CDMO organization. Responsible for driving execution of Drug Product production plans Provide operational oversight and troubleshooting support to ensure all deliverables meet or exceed Vertex requirements (including but not limited to successful execution of manufacturi

Perform in process, release, and stability testing and/or review independently following established methodology, procedures and SOPs Maintain accurate testing records and adhere to cGMP/GDP expectations May participate in executing method validations and/or method transfers Assist in troubleshooting of analytical methods with the assistance of manager when necessary May

Lead the design and execution of experiments for cell therapy process development , including cell banking , cell culture, harvest, and formulation Perform independent analysis and p resent to internal team as well as broader program teams Evaluate and implement novel technologies and equipment platforms for next generation cell therapy manufacturing processes such as cel